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The possible role of brain histamine and H1and H2receptors in the development of morphine tolerance and physical dependence in mice

✍ Scribed by Chak-Lam Wong; Michael B. Roberts

Publisher
SP Birkhäuser Verlag Basel
Year
1975
Tongue
English
Weight
670 KB
Volume
5
Category
Article
ISSN
1420-908X

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The effects of pyrilamine and burimamide (histamine HIand H2-receptor blockers, respectively) on the hypothermic response to histidine loading have been studied in rats. The antagonists were injected into one of three sites in the brain: the preoptic/ anterior hypothalamic nuclei, the lateral ventri