The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease
โ Scribed by Rossetti, S.
- Book ID
- 115470100
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2002
- Tongue
- English
- Weight
- 362 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1046-6673
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๐ SIMILAR VOLUMES
Since identification of the genes mutated in patients with Autosomal Dominant Polycystic Kidney Disease, PKD1 and PKD2, a large number of different germ line mutations in both genes have been found by conventional PCR-based mutation detection methods. Nevertheless, in approximately 40% of the PKD1 f
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited nephropathy, usually of late onset (onset between third to seventh decade), primarily characterized by the formation of fluid-filled cysts in the kidneys. It is one of the most frequent inherited conditions affecting approximately