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The Polymorphism of Platelet Membrane Integrin α2β1 (α2 807TT) is Associated with Premature Onset of Fetal Loss

✍ Scribed by Gerhardt, Andrea; Scharf, Rüdiger E.; Mikat-Drozdzynski, Barbara; Krüssel, Jan S.; Bender, Hans G.; Zotz, Rainer B.


Book ID
115499560
Publisher
Schattauer
Year
2005
Tongue
English
Weight
265 KB
Volume
93
Category
Article
ISSN
0340-6245

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The interindividual pharmacokinetic variability of the a 4 b 1 integrin antagonist -4582) was observed in beagles. The involvement of albumin genetic polymorphism in this variability was investigated. The albumin genotype was analyzed by sequencing the albumin gene from liver and blood samples. The