Sterol regulatory element binding protein 1 (SREBP-1) transcription factors play a key role in energy homeostasis by regulating genes involved in both carbohydrate and lipid metabolism, and in adipocyte differentiation. The 5' end of the mRNA-encoding SREBP-1 exists in two forms, designated 1a and 1
✦ LIBER ✦
The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans
✍ Scribed by S.-P. Choukem; P. Boudou; E. Sobngwi; J.-M. Villette; F. Ibrahim; P. Moulin; S. Hadjadj; D. Eberle; F. Foufelle; P. Vexiau; J.-F. Gautier
- Book ID
- 116404782
- Publisher
- Masson Editeur
- Year
- 2009
- Tongue
- French
- Weight
- 169 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1262-3636
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## Background: The peroxisome proliferator-activated receptor-gamma (ppargamma) gene has been recently associated with type 2 diabetes, obesity and traits depending on vegf expression (e.g. retinopathy). the ppargamma gene and its coactivator, the peroxisome proliferator-activated receptor-gamma co