Involvement of the N-methyl-D-aspartate
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Ursula Malipiero; Christian Heuss; Ralph Schlapbach; JΓΌrg Tschopp; Urs Gerber; A
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Article
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1999
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John Wiley and Sons
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English
β 347 KB
π 2 views
The mechanisms underlying neurotoxicity mediated by cytotoxic T lymphocytes (CTL) and their secretory granule proteins perforin and granzymes remain unclear. We evaluated the possible role of the neurotransmitter glutamate in cell death observed in differentiated neurons exposed to CTL-derived granu