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The Plasma Membrane Ca2+ ATPase and the Plasma Membrane Sodium Calcium Exchanger Cooperate in the Regulation of Cell Calcium

✍ Scribed by Brini, M.; Carafoli, E.


Book ID
111916154
Publisher
Cold Spring Harbor Laboratory
Year
2010
Tongue
English
Weight
898 KB
Volume
3
Category
Article
ISSN
1943-0264

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## Abstract The human mast cell line (HMC‐1) has been used to study the relationship between intracellular pH and cytosolic calcium (Ca^2+^) in mast cells. Thapsigargin (TG) caused store‐operated Ca^2+^ entry, that is enhanced by the PKC activator PMA. NH~4~Cl‐induced alkalinization showed an inhib