The plasma kallikrein–kinin system and risk of cardiovascular disease in men
✍ Scribed by J. W. P. GOVERS-RIEMSLAG; M. SMID; J. A. COOPER; K. A. BAUER; R. D. ROSENBERG; C. E. HACK; K. HAMULYAK; H. M. H. SPRONK; G. J. MILLER; H. TEN CATE
- Book ID
- 109152252
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 507 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1538-7933
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The kallikrein-kinin system (KKS) plays an important role in the regulation of renal function. Endogenous kinins modulate renal microvascular resistance, medullary blood flow, and distal nephron sodium and water reabsorption. All the components of the KKS, including tissue kallikrein, kininogen, kin
The activity of both the coagulation and fibrinolytic systems was markedly depressed 24 h after a sublethal dose of T-2 toxin. T-2 toxin was active as an anticoagulant at low doses, which did not affect the basal state of the animals. The kallikrein-kinin system was also affected by depletion of the