The pineal gland as an APUD organ: Supporting evidence and implications
β Scribed by Leong, A.S.Y.; Matthews, C.D.
- Book ID
- 121953664
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 720 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0306-9877
No coin nor oath required. For personal study only.
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An attempt was made to use the pineal gland as a model for the study of the primary mode of action of alpha-methyldopa, which is still unclear. Organ cultures of pineal glands from rats treated chronically with alpha-methyldopa showed enhanced conversion of radio-active serotonin to melatonin (aMT)
## Abstract Male rats (25β26 days of age) housed with 14 hours of light per day (lights on 0600β2000 hours) were either olfactory bulbectomized (rendering them anosmic), bulbectomized plus pinealectomized (Pinx), or left intact. On the day following the operations, intact, anosmic, and anosmicβPinx