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The pigeon pattern electroretinogram is not affected by massive loss of cell bodies in the ganglion layer induced by chronic section of the optic nerve

โœ Scribed by V. Porciatti; W. Francesconi; P. Bagnoli


Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
402 KB
Volume
61
Category
Article
ISSN
0012-4486

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โœฆ Synopsis


In pigeons, electroretinographic responses to contrast reversal of sinusoidal gratings (pattern ERGs) were recorded before and after section of the left optic nerve. Ninety and 270 days following optic nerve section the ganglion cell layer of the side that underwent the surgical procedure showed an 80% reduction in the number of cell bodies as compared with the intact side. At these times the pattern ERGs showed comparable iamplitudes in both eyes. There is a possibility that the inne} nuclear layer of the pigeon retina plays a major role in the generation of the pattern ERG.


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We estimated cell numbers in the ganglion cell and inner nuclear layers of adult frog (Hyla moorei) retinae, examining normal animals and those with regenerated optic nerves. Analysis of sections stained with cresyl violet showed that cell numbers in a nasotemporal strip, which included the area cen