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The PI3K/Akt/mTOR pathway mediates retinal progenitor cell survival under hypoxic and superoxide stress

โœ Scribed by Karan P. Sanghera; Nurit Mathalone; Ramteen Baigi; Elan Panov; Dan Wang; Xu Zhao; Howard Hsu; Hai Wang; Vincent Tropepe; Michael Ward; Shelley R. Boyd


Book ID
116735661
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
1002 KB
Volume
47
Category
Article
ISSN
1044-7431

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## Abstract Neural stem/progenitor cells (NS/PCs) have been studied extensively with the hope of using them clinically to repair the damaged central nervous system. However, little is known about the signals that regulate the proliferation, survival, and differentiation of NS/PCs in early developme