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The PI3K/Akt pathway differentially regulates apoptotic and survival mechanims in primary mouse hepatocytes and hepatocellular carcinoma cell lines

✍ Scribed by T. Nitta; S. Lyman; K.E. Behrns


Book ID
116702411
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
116 KB
Volume
130
Category
Article
ISSN
0022-4804

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## Abstract Human intestinal epithelial cell survival and anoikis are distinctively regulated according to the state of differentiation. In the present study, we analyzed the roles of focal adhesion kinase (Fak)/Src signaling to the PI3‐K/Akt‐1 and mitogen‐activated protein kinase (MEK)/extracellul