## Abstract The pedunculopontine nucleus is composed of cholinergic and non‐cholinergic neurones and is located in the caudal pontomesencephalic tegmentum. Evidence suggests that the nucleus plays a role in the production and control of movement. The nucleus has dense interconnections with the basa
The physiology and pathology of inositide signaling in the nucleus
✍ Scribed by Giulia Ramazzotti; Irene Faenza; Roberta Fiume; Alessandro Matteucci; Manuela Piazzi; Matilde Yung Follo; Lucio Cocco
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 147 KB
- Volume
- 226
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Nuclear inositide signaling is nowadays a well‐established issue and a growing field of investigation, even though the very first evidence came out at the end of the 1980's. The understanding of its biological role is supported by the recent acquisitions dealing with pathology and namely hematological malignancies. Here, we review this issue highlighting the main achievements in the last years. J. Cell. Physiol. 226: 14–20, 2010. © 2010 Wiley‐Liss, Inc.
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