The physical state of HPV16 infection and its clinical significance in cancer precursor lesion and cervical carcinoma
โ Scribed by Wei Li; Wei Wang; Mani Si; Linfei Han; Qinglei Gao; Aiyue Luo; Yan Li; Yunping Lu; Shixuan Wang; Ding Ma
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 351 KB
- Volume
- 134
- Category
- Article
- ISSN
- 1432-1335
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The object of our study is to project the impact of a prophylactic vaccine against persistent human papillomavirus (HPV)-16/18 infection on age-specific incidence of invasive cervical cancer. We developed a computer-based mathematical model of the natural history of cervical carcinogenesis to incorp
## Abstract The presence of HPV 16 E6\*I/E6\*II spliced transcripts, in cervical lesions of different grade, was analyzed to characterize the transcription pattern. The presence and amount of spliced transcripts were correlated with DNA viral markers such as E2/E6 ratio and physical state. The dete