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The phylogeny of the aromatic amino acid hydroxylases revisited by characterizing phenylalanine hydroxylase from Dictyostelium discoideum

✍ Scribed by Jessica Siltberg-Liberles; Ida Helene Steen; Randi M. Svebak; Aurora Martinez


Book ID
116508137
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
947 KB
Volume
427
Category
Article
ISSN
0378-1119

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Aromatic l-amino acid decarboxylase (AADC) and tyrosine hydroxylase (TH) are involved in the synthesis of dopamine and other monoamine neurotransmitters, and their activities can be regulated by a number of physiological stimuli. An interesting finding has been that (2)-deprenyl and some other irrev