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The phototoxicity of photofrin was enhanced by PEGylated liposome in vitro

✍ Scribed by Yasuyuki Sadzuka; Koji Tokutomi; Fumiaki Iwasaki; Ikumi Sugiyama; Toru Hirano; Hiroyuki Konno; Naoto Oku; Takashi Sonobe

Book ID
116334010
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
225 KB
Volume
241
Category
Article
ISSN
0304-3835

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## Abstract **Introduction:** Nanoscale particle‐based drug delivery systems like long circulating liposomal doxorubicin show unique pharmacokinetic properties and improved toxicity profiles. Liposomal doxorubicin accumulates in tumor tissue due to the enhanced permeation and retention effect, but