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The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells

โœ Scribed by Jung Sun Kim; Byung Soo Kim; Jiha Kim; Choon-Sik Park; Il Yup Chung


Book ID
107642294
Publisher
Springer
Year
2010
Tongue
English
Weight
566 KB
Volume
33
Category
Article
ISSN
0253-6269

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## Abstract Elevated expression of p130^Cas^/BCAR1 (breast cancer anti estrogen resistance 1) in human breast tumors is a marker of poor prognosis and poor overall survival. Specifically, p130^Cas^ signaling has been associated with antiestrogen resistance, for which the mechanism is currently unkn