The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis
β Scribed by Tatiana Kisseleva; David A. Brenner
- Book ID
- 116652632
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 911 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
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## Abstract ## Background Bone marrowβderived liver stem cells (BDLSCs) are very robust cells that can differentiate into liver epithelial cells. These stem cells are promising targets for gene therapy treatment of liver diseases. Liver fibrosis results from chronic liver damage characterized by a
Hematopoietic stem cells have potential in the field of regenerative medicine because of their capacity to form cells of different lineages. Bone marrow stem cells have been shown to contribute to parenchymal liver cell populations, and although this may not be functionally significant, it has spark
Mesenchymal stem cells (MSCs) have received much attention for their ability to differentiate into various cell types under specific conditions and to support the proliferation of hematopoietic stem cells. However, it is unclear whether the characteristics of MSCs are altered in different disease st