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The pharmacological characterisation of pilocarpine-induced purposeless chewing behaviour in the rat

✍ Scribed by Brian R. Stewart; Peter Jenner; C. David Marsden

Publisher
Springer
Year
1988
Tongue
English
Weight
876 KB
Volume
96
Category
Article
ISSN
0033-3158

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Behavioural and pharmacological characte
Behavioural and pharmacological characterization of the mouth movements induced by muscarinic agonists in the rat
✍ J. D. Salamone; M. D. Lalies; S. L. Channell; S. D. Iversen πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 517 KB

Pilocarpine administered in doses of 1.25-10.0 mg/kg (IP) produced a variety of mouth movements in the rat. The most frequent of these movements was a chewing behaviour, which increased up to a mean frequency of over 40 per min at the highest doses. Tongue protrusion and gaping also showed dose-depe