Pharmacokinetics and material balance st
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Hon-Wing Leung; Tipton R. Tyler
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Article
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1997
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John Wiley and Sons
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English
⚖ 82 KB
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The metabolism and disposition of diethylenetriamine trihydrochloride (DETA•3HCl) were studied with regard to route of administration and dosage effects. Male Fischer 344 rats were administered 50 or 500 mg kg -1 of [1,2-14 C]-DETA•3HCl orally or endotracheally, and the fate of the 14 C-radioactivit