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The pharmacokinetics of ketorolac enantiomers following intramuscular administration of the racemate.

โœ Scribed by Hayball, PJ (author);Wrobel, J. (author);Tamblyn, JG (author);Nation, RL (author)

Book ID
117945557
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
551 KB
Volume
37
Category
Article
ISSN
0306-5251

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To determine the stereospecific pharmacokinetics and gastrointestinal permeability (GI) changes (surrogate measures of toxicity) in the rat following oral administration of S, R, and racemic ketorolac (KT),optically pure enantiomers (S and R 2.5 mg/kg), and racemic KT (5 mg/kg) were administered ora