Nicardipine HCI oral doses (10-40 mg) were administered sequentially to six healthy subjects. For each regimen the capsule dose was administered every 8 hours (q 8 h) for 3 days and the plasma profiles of nicardipine and its pyridine analogue (M5) were determined following the last dose on day 4. St
The pharmacokinetics of ketanserin after a single dose and at steady-state in hypertensive subjects
β Scribed by P. C. Waller; G. T. Tucker; L. E. Ramsay
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 372 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0031-6970
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Serum and urine kinetics of unchanged tiracizine (T), a new class I antiarrhythmic agent, and three metabolites (Ml, 2, and 3) were assessed in eight healthy extensive metabolizers after a single oral administration of 50 mg tiracizine and during steady state (50 mg b.i.d.). Additionally, tiracizine
## Abstract Nine patients taking oral doses of 10 mg/12 h racβpindolol as part of their treatment for hypertension in pregnancy were recruited for the study. Maternal and fetal gestational age ranged from 20β38 years and 28β41 weeks, respectively. Blood was collected from the umbilical cord vein an