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The pharmacokinetics of glyceryl trinitrate with the use of the in vitro term human placental perfusion setup

✍ Scribed by Mark A. Bustard; Anne E. Farley; Graeme N. Smith


Book ID
114487788
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
77 KB
Volume
187
Category
Article
ISSN
1097-6868

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The objectives of this study were to evaluate the transplacental kinetics and effects on placental function of the angiotensin converting enzyme (ACE) inhibitor, enalaprilat, in the dually perfused human placental lobule system. When placed in the maternal perfusate at a high therapeutic serum conce