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The pharmacokinetics of amiloride-hydrochlorothiazide combination in the young and elderly

โœ Scribed by Z. Ismail; E. J. Triggs; B. A. Smithurst; W. Parke


Publisher
Springer
Year
1989
Tongue
English
Weight
616 KB
Volume
37
Category
Article
ISSN
0031-6970

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Diltiazem and hydrochlorothiazide are widely used to treat cardiovascular disease, often in combination. The purpose of this investigation was to determine whether a drug -drug pharmacokinetic interaction exists between diltiazem and hydrochlorothiazide. In a randomized, crossover, open study, multi