The pharmacokinetic behavior of the photosensitizermeso-tetra-hydroxyphenyl-chlorin in mice and men
β Scribed by Martijn Triesscheijn; Marjan Ruevekamp; Ruud Out; Theo J. C. Van Berkel; Jan Schellens; Paul Baas; Fiona A. Stewart
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 488 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To optimize photodynamic therapy (PDT) and photodetection of cancer with second-generation photosensitizers, knowledge of important variables such as the uptake of the dye and the dye contrast between normal and tumoral tissue after injection is necessary. The pharmacokinetics of a secondgeneration
Photodynamic therapy (PDT) produces localised necrosis with light after prior administration of a photosensitising drug. Although the technique is promising for small tumours of hollow organs, little work has been done on solid organs like the prostate. We studied the tissue biodistribution and phot
Balb/c athymic nude mice bearing WiDr human colon adenocarcinoma have been employed to investigate the effect of glucose administration, cooling or slight heating on the anti-tumor activity of photochemotherapy (PCT) with meso-tetra-hydroxyphenyl-chlorin (mTHPC). An apparent delay in the tumor growt