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The pharmacodynamic and pharmacokinetic profiles of controlled-release formulations of felodipine and metoprolol in free and fixed combinations in elderly hypertensive patients

✍ Scribed by J.S. McLay; T.M. MacDonald; J. Hosie; H.L. Elliott


Publisher
Springer
Year
2000
Tongue
English
Weight
107 KB
Volume
56
Category
Article
ISSN
0031-6970

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The pharmacokinetics and pharmacodynamic
✍ P. Lundborg; B. Abrahamsson; I. Wieselgren; M. Walter πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 302 KB

We have studied a controlled-release formulation containing metoprolol 100 mg and hydrochlorothiazide 12.5 mg. We compared the pharmacokinetics of both substances and the pharmacodynamics of metoprolol with those of a conventional combination tablet. The controlled-release formulation gave less vari