The permeability of living cells to heavy water (deuterium oxide)
- Book ID
- 112636569
- Publisher
- Springer Vienna
- Year
- 1936
- Tongue
- English
- Weight
- 92 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0033-183X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## ONE FIGURE The isolation of deuterium oxide (heavy water) in relatively pure form immediately suggested studies of its biological effects. Since the first report of such a study (Lewis, '33) many papers dealing with this field have been published, and these have been reviewed more or less compl
Using a stopped-flow device, the osmotic water permeability of human red cells to D,O and H,O was studied as a function of temperature and under the influence of the sulfhydryl reagent paracholoromercuribenzene sulfonic acid (PCMBS), an inhibitor of water transport. The ratio, permeability (D,O)/ pe
Since deuterium oxide differs from water in respect to its viscosity and the mobility of its molecules, it might be expected that these differences would influence its rate of penetration into living cells. Luck6 and Harvey ( ' 3 5 ) have given a detailed discussion of this possibility in their comp