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The periaqueductal grey matter modulates trigeminovascular input: a role in migraine?

โœ Scribed by Y.E Knight; P.J Goadsby


Book ID
117490227
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
175 KB
Volume
106
Category
Article
ISSN
0306-4522

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In rats anaesthetised with alphaxalone/alphadolone, electrical stimulation in the dorsal periaqueductal grey matter (PAG) evoked a pressor response with tachycardia, vasodilatation in the hindlimb and hyperpnoea: a pattern of response known as the defence reaction. Microinjection of the synaptic exc