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THE PENETRATION OF DAPSONE, RIFAMPICIN, ISONIAZID AND PYRAZINAMIDE INTO PERIPHERAL NERVES

โœ Scribed by B.W. ALLEN; G.A. ELLARD; PATRICIA T. GAMMON; R.C. KING; A.C. McDOUGALL; R.J.W. REES; A.G.M. WEDDELL

Book ID
117956781
Publisher
Nature Publishing Group
Year
1975
Tongue
English
Weight
734 KB
Volume
55
Category
Article
ISSN
0007-1188

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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo