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The PDZ protein discs-large (DLG): the ‘Jekyll and Hyde’ of the epithelial polarity proteins

✍ Scribed by Sally Roberts; Craig Delury; Elizabeth Marsh

Book ID
117964099
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
191 KB
Volume
279
Category
Article
ISSN
1432-1327

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## Abstract **Background:** Recent studies have revealed that aPKC (atypical protein kinase C), PAR‐3 and PAR‐6 play indispensable roles in the regulation of various cell polarization events, from worms to mammals, suggesting that they comprise an evolutionarily conserved protein machinery which is