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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

✍ Scribed by Campbell, Peter J.; Yachida, Shinichi; Mudie, Laura J.; Stephens, Philip J.; Pleasance, Erin D.; Stebbings, Lucy A.; Morsberger, Laura A.; Latimer, Calli; McLaren, Stuart; Lin, Meng-Lay

Book ID
109899216
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
435 KB
Volume
467
Category
Article
ISSN
0028-0836

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## Abstract Genomic alterations influencing the expression and/or activity of tumor suppressors or oncogenes such as __KRAS2__, __CDKN2A__, __TP53,__ and __DPC4__ have been directly implicated in the initiation and progression of human pancreatic adenocarcinoma. In an effort further to systematical