The pathophysiology of penicillamine-induced myasthenia gravis
β Scribed by Dr Ralph W. Kuncl; Alan Pestronk; Daniel B. Drachman; Emanuel Rechthand
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 563 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0364-5134
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π SIMILAR VOLUMES
Myasthenia gravis (MG) and its animal model experimental autoimmune myasthenia gravis (EAMG) are caused by autoantibodies against nicotinic acetylcholine receptor (AChR) in skeletal muscle. The production of anti-AChR antibodies is mediated by cytokines produced by CD4+ and CD8+ T helper (Th) cells.
## Abstract We report our experience with singleβfiber electromyogrphy (SFβEMG), acetylcholine receptor antibody assays, and Lancaster RedβGreen tests of ocular motility with edrophonium chloride in the diagnosis of myasthenia gravis (MG). Over a period of almost 3 years, 43 patients in whom repeti