Using biochemical and immunocytochemical methods, we have investigated endogenous levels of various markers in tissues obtained from 67 Down's syndrome pregnancies after therapeutic abortion in the second trimester and in corresponding tissues from unaffected abortuses. Alpha-fetoprotein (AFP), inta
โฆ LIBER โฆ
The pathophysiology of Down's syndrome pregnancies
โ Scribed by D. Newby; D.A. Aitken; J.A. Crossley; A.G. Howatson; J.M. Connor
- Book ID
- 114247911
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 112 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0378-3782
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Protein S100 is a low molecular weight (10-12 kD) calcium-binding protein the beta subunit of which is coded for at the 22.2-22.3 region of the long arm of chromosome 21. This region has also been shown to be responsible for the phenotypic expression of Down syndrome. Previous studies demonstrated i