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The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2

✍ Scribed by Lakhani, S. R.

Book ID
118150252
Publisher
American Society of Clinical Oncology
Year
2002
Tongue
English
Weight
80 KB
Volume
20
Category
Article
ISSN
0732-183X

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## Abstract The breast cancer susceptibility genes __BRCA1__ and __BRCA2__ are responsible for a large proportion of familial breast and ovarian cancer, yet little is known of how disruptions in the functions of the proteins these genes encode increased cancer risk preferentially in hormone‐depende