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The pathogenesis of liver injury in carbon tetrachloride and thioacetamide poisoning

โœ Scribed by Rees, K. R. ;Sinha, K. P. ;Spector, W. G.


Publisher
Wiley (John Wiley & Sons)
Year
1961
Tongue
English
Weight
662 KB
Volume
81
Category
Article
ISSN
0368-3494

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โœ Dolak, James A. ;Waller, Robert L. ;Glende, Eric A. ;Recknagel, Richard O. ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 770 KB

The calcium fluorescent probe fura2 was used to measure concentration of free calcium in the cytosol of isolated rat hepatocytes in suspension. The resting level in untreated hepatocytes was 121 nM. On addition of CCl4 at a concentration of 0.5 mM, cytosolic free calcium rose sharply and reached a s