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The partial dopamine receptor agonist terguride in the MPTP-induced hemiparkinsonian monkey model

✍ Scribed by Thomas Brücke; Krzysztof Bankiewicz; Judith Harvey-White; Irwin Kopin


Book ID
115881337
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
284 KB
Volume
148
Category
Article
ISSN
0014-2999

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Exposure to l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP) can cause an acute chemical toxicity resulting in a parkinsonian state in humans and nonhuman primates. We wished to assess whether the toxicity from MPTP is associated with changes on magnetic resonance images of brain structures conta