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The ParaSight™-F test for detecting treatment failure: a reply

✍ Scribed by Juntra Karbwang

Book ID
104164682
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
157 KB
Volume
91
Category
Article
ISSN
0035-9203

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✦ Synopsis

CORRESPONDENCE 491 rapidly, might have led to more rapid clearance of HRP-2. With chloroquine, which acts less rapidly, antigenaemia may have persisted longer, and this could account for the disparity in findings. The utility of the Par-aSighP-F test as a diagnostic tool for the detection of treatment failures would thus depend on the antimalarial drug being used and also probably on the country of use, since the kinetics of HRP-2 during the decline phase of malaria and the effect of the immune status of the individual are not yet completely understood.

Although our sample was small, our own feeling is that treating all patients with a positive PuruSightTM-F test on day 15 may result in a large number of patients receiving 'rescue' medication when it is not warranted.

s. vakharia' N.

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