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The P2X1 receptor and platelet function

✍ Scribed by Martyn P. Mahaut-Smith; Sarah Jones; Richard J. Evans

Publisher: Springer Netherlands
Year: 2011
Tongue: English
Weight: 694 KB
Volume: 7
Category: Article
ISSN: 1573-9538
DOI: 10.1007/s11302-011-9224-0

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## Abstract The recent generation of mice deficient for the P2Y~1~ receptor has allowed us to directly examine the contribution of this nucleotide receptor in ADP‐induced aggregation both in isolated platelets and in vivo thrombosis. Studies utilizing the P2Y~1~‐deficient platelets clearly demonstr