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The p16INK4a/CDKN2A tumor suppressor and its relatives

✍ Scribed by Margarida Ruas; Gordon Peters

Book ID
114222971
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
538 KB
Volume
1378
Category
Article
ISSN
0304-419X

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## Abstract The prevalence of __p16__^__INK4A__^__/Cdkn2a__ genetic alterations in human oral cancers indicates that the __p16__ gene could be a potent and appropriate target for novel intervention. While chemically induced hamster cheek pouch (HCP) tumors are regarded as an appropriate surrogate m