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The oxygen affinity of sickle hemoglobin

✍ Scribed by Amgad Abdu; José Gómez-Márquez; Thomas K. Aldrich


Book ID
116861553
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
111 KB
Volume
161
Category
Article
ISSN
1569-9048

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An important purpose of blood transfusion in patients with sickle cell disease is to improve arterial oxygen saturation (SaO 2 ) and thereby reduce red cell sickling. To investigate the degree of improvement in SaO 2 by blood transfusion, we determined the hemoglobin oxygen affinity, transcutaneous