The oxidative co-coupling of phenols. The synthesis of tetrahydrodibenzofuranones

✍ Scribed by Clive W. Bird; Yesh-Pal S. Chauhan

• Publisher: Elsevier Science
• Year: 1978
• Tongue: French
• Weight: 139 KB
• Volume: 19
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)94770-7

✦ Synopsis

2 contrast to the extensive examples of oxidative self-coupling of monohydric phenols', reports of successful oxidative coupling of dissimilar phenols are very limited. Apart from the minor products resulting from ferric chloride oxidation of p-cresol* the only other intermolecular examples are provided by the recently reported3 co-oxidation of p-cresol with 2,bdimethyl and 2,4,6_trimethylphenol. This communication sumnarises some of our observations in this area with particular reference to the synthesis of tetrahydrodibenzofuranones.