The osteogenic-angiogenic interface: Novel insights into the biology of bone formation and fracture repair

Enhanced fracture repair by leukotriene

Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: A novel role of the cysteinyl LT-1 receptor

✍ John J. Wixted; Paul J. Fanning; Tripti Gaur; Shannon L. O'Connell; Jason Silva; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 429 KB

## Abstract Inflammatory mediators and drugs which affect inflammation can influence the healing of injured tissues. Leukotrienes are potent inflammatory mediators, and similar to prostaglandins, are metabolites of arachidonic acid which can have positive or negative effects on bone and cartilage t