𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

✍ Scribed by Ivaylo I. Ivanov; Brent S. McKenzie; Liang Zhou; Carlos E. Tadokoro; Alice Lepelley; Juan J. Lafaille; Daniel J. Cua; Dan R. Littman

Book ID
116353213
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
1004 KB
Volume
126
Category
Article
ISSN
0092-8674

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

RORγT, a thymus-specific isoform of the
RORγT, a thymus-specific isoform of the orphan nuclear receptor RORγ / TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter
✍ Isabelle Villey; Régina de Chasseval; Jean-Pierre de Villartay 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 1 views

TEA (T early alpha) is a genetic element located upstream of the TCR-J § cluster. Thymocytes from mice carrying a targeted deletion of TEA do not rearrange their TCR § locus on a window spanning the first nine J § segments. This led us to the hypothesis of TEA having a "rearrangement focusing" activ