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The origin of the major cystic fibrosis mutation (ΔF508) in European populations

✍ Scribed by Morral, N.; Bertranpetit, J.; Estivill, X.; Nunes, V.; Casals, T.; Giménez, J.; Reis, A.; Varon-Mateeva, R.; Macek, M.; Kalaydjieva, L.


Book ID
109916225
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
675 KB
Volume
7
Category
Article
ISSN
1061-4036

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The cystic fibrosis ΔF508 gene mutation
✍ Rose Ann Padua; Neil Warren; David Grimshaw; Melissa Smith; Christopher Lewis; J 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB

Following the observation that relatives of cystic fibrosis (CF) patients have an increased mortality due to leukaemia, a study was initiated to determine whether leukaemia patients had an increased prevalence of the DF508 CF mutation. No increase in carriers were found among leukaemias; however the