The origin of the Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin's disease and their relationship to HRS-like cells occuring in B-cell chronic lymphatic leukemia
✍ Scribed by H. Kanzler; R. Küppers; S. Helmes; M.-L. Hansmann; K. Rajewsky
- Book ID
- 108409108
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 181 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0165-2478
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## Abstract We discuss nine cases identified at our institution with prominent Reed‐Sternberg‐like cells in fine‐needle aspiration of lymph nodes in patients without Hodgkin's disease. Cytomorphology was studied using Diff‐Quik and Papanicolaou‐stained smears and flow cytometric analysis was perfor
## Epstein-Barr virus (EBV) is detected in Hodgkin and Reed-Sternberg (HRS) cells in up to 50% of patients with Hodgkin's disease (HD). HD patients have been reported to express high serum titers against EBV antigens, even prior to the diagnosis of HD. Patients with high serum titers have a poorer