The Origin of Stereoselectivity in Primary Amino Acid Catalyzed Intermolecular Aldol Reactions
✍ Scribed by Arianna Bassan; Weibiao Zou; Efraim Reyes; Fahmi Himo; Armando Córdova
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 171 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0044-8249
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📜 SIMILAR VOLUMES
The catalytic properties of all proteinogenic, acyclic amino acids for direct aldol reaction in H 2 O, assisted by various surfactants, were investigated. The basic and neutral amino acids were shown to be efficient catalysts, giving rise to good-to-excellent yields of adducts (up to 95%), with mode
## Abstract A variety of amino acid‐derived water‐soluble primary‐tertiary diamines is prepared and successfully applied as organocatalyst in the aldol reaction of protected hydroxyacetone derivatives (I) and (IV) with aromatic aldehydes.