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The origin of quasispecies: cause or consequence of chronic hepatitis C viral infection?

✍ Scribed by David G. Bowen; Christopher M. Walker


Book ID
116650606
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
210 KB
Volume
42
Category
Article
ISSN
0168-8278

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To determine the clinical significance of viral quasispecies heterogeneity, 59 patients with chronic hepatitis C were studied using singlestranded conformational polymorphism (SSCP) analysis of the HCV E2 hypervariable region 1 (HVRI); of these, 48 were subsequently treated with interferon-a. The SS