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The Origin of Antimicrobial Resistance and Fluidity Dependent Membrane Structural Transformation by Antimicrobial Peptide Protegrin-1

✍ Scribed by Chapman, Matthew R.; Lam, Kin Lok H.; Waring, Alan J.; Lehrer, Robert I.; Lee, Ka Yee C.


Book ID
122296023
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
41 KB
Volume
96
Category
Article
ISSN
0006-3495

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## Abstract The interaction of protegrin‐1 (PG‐1), a small β‐sheet antimicrobial peptide with acidic phospholipid model membranes was investigated by differential scanning calorimetry. We found that PG‐1 can distinguish between liposomes of the anionic phospholipids DPPG, DPPS and DPPA, eventhough