The One-Pot Wittig Reaction: A Facile Synthesis of α,β-Unsaturated Esters and Nitriles by Using Nanocrystalline Magnesium Oxide.
✍ Scribed by Boyapati M. Choudary; Koosam Mahendar; M. Lakshmi Kantam; Kalluri V. S. Ranganath; Taimur Athar
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 39 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract Aldol‐type reaction between electron deficient aldehydes and sulfonium salts to afford the corresponding __β__‐hydroxy __α__‐sulfanyl esters in moderate‐to‐good yields by using nanocrystalline MgO is described. The sulfanyl group is a useful group for further transformations in organic
N-t-Butylacetamidines 1 on heating with methyl acrylate (2) at 200˚ gave the 4,5-dihydro-3H-pyridin-2one derivatives 5. Michael addition of the acetamidines 1 as their ene-1,1-diamine tautomers 1' to 2 and the subsequent cyclization of the adducts gave derivatives 5. Amidines 1 on reaction with trim