The Official Tests for Creosote

✍ Scribed by England, Joseph W.

• Publisher: Elsevier
• Year: 1912
• Weight: 265 KB
• Volume: 1
• Category: Article
• ISSN: 0898-140X
• DOI: 10.1002/jps.3080010408

✦ Synopsis

The tests of the G. S. Pharmacopceia (VIII) for Creosote are indefinite and unsatisfactory.

The therapeutically active ingredients are chiefly the ethers guaiacol (b.p. 200" C.) and creosol (b.p. 219" C.) with the alcohols phenol (b.p. 182" C. B. P.), paracreosol (b.p. 203" C.) , dimethyl-guaiacol (b.p. 230" C.) and propyl-guaiacol (b.p. 241" C.), (Food and Drugs, E. J. Parry, 1911, 454). Guaiacol and creosol are closely related, chemically, the former being methyl catecholate (C,H, (OCH,OH) ),'and the latter, methyl homocatecholate (C,H,CH, (OCH,OH) ).