Determination of the free concentration
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Pernilla Koivisto; Sara K. Bergström; Karin E. Markides
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Article
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2001
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John Wiley and Sons
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English
⚖ 97 KB
## Abstract In this study, ultrafiltration and microdialysis have been compared as sample preparation methods to separate the free fraction of ropivacaine from the protein bound in 150 μL plasma. A liquid chromatographic system with packed capillary columns (0.2 mm internal diameter) was used to en